Menstruation Research - Menstrual Cycle, Pregnancy, Pain, Irregular Menstruation

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Length of the menstrual cycle after discontinuation of oral contraceptives.

Duijkers I, Engels L, Klipping C

Dinox Medical Investigations, Nijmengen, The Netherlands. iduijkers@dinoxgroup.com

OBJECTIVE: To investigate whether the first cycle after stopping oral contraceptive (OC) intake had a normal duration. METHODS: A retrospective study was performed in 680 women, 300 non-OC users and 380 women discontinuing OC intake. The length of one or two menstrual cycles was recorded. RESULTS: In the non-user group, the median duration of both the first and second cycle was 29 days (range 18-97 and 20-56 days, respectively). In the OC user group the median duration from withdrawal bleeding until next menstruation was 30 (15-82) days. The second cycle lasted 29 (17-122) days. The duration of the first post-treatment cycle was not significantly different from the next cycle or the cycle length in non-users. When the subjects were divided into different age categories, a significantly longer first post-treatment cycle was observed in the group aged 18-24 years, but a shorter first post-treatment cycle in the group aged 25-29 years. No differences were seen in the higher age groups. The ethinyl estradiol dose of the OC preparation did not influence the results. CONCLUSIONS: The first cycle after OC discontinuation had a normal duration.

Published 12 April 2005 in Gynecol Endocrinol, 20(2): 74-9.
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